Your testing partner for human pluripotent stem cells (hPSCs)
IDEXX BioAnalytics is now proud to offer the fastest copy number variant genomic testing assay available. Detect over 90% of recurrent abnormalities in hPSCs in as little as three days!
Human Pluripotent Stem Cells (hPSCs) are quite susceptible to acquiring abnormalities while in culture. Within just five passages or fewer, these variations can become prevalent, potentially jeopardizing the integrity of your research.
Our partners, STEM GENOMICS, have developed a fast, sensitive, ddPCR-based assay that we are pleased to perform in our North American lab.
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Our holistic approach to hPSC health
In their most recent guidance (June 2023), the ISSCR recommends characterizing hPSCs by testing them at regular intervals. This includes STR profiling to confirm cell line identity at the initial characterization of the master cell bank, as well as STR and iPSC-digital PSC testing at any significant stress or bottleneck (i.e., gene editing), and at the end of the study.
Protect your research: As a partner in your holistic approach to cell health, IDEXX BioAnalytics recommends careful testing of hPSC populations using iCS-digital™ PSC, CellCheck (STR Testing), h-IMPACT (human virus screening), STAT-Myco (mycoplasma spp screen), and sterility testing (microbial contaminants).
Original Source: STEM GENOMICS